Oprah Winfrey and Reese Witherspoon are apparently the next generation of mutants all thanks to what some think is a Photoshop fail.

Vanity Fair released its annual Hollywood issue and right in the middle of the cover photo of Tinsel Town elite, an Oscar-winning star seems to have sprouted an extra leg, Entertainment Tonight reported.

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Reese Witherspoon is taking to having the extra appendage in stride.

Vanity Fair responded, saying that the extra leg is actually fabric from her dress.

But a behind-the-scenes picture can't be waved off so easily. In it Witherspoon is next to Winfrey and it appears that the media mogul has one hand on her hip, one on her leg and a third around Witherspoon's waist. The pair star in this year's "A Wrinkle In Time," the Daily Mail reported.

Winfrey didn’t ignore the extra hand either, also taking to Twitter to respond to Reese’s extra leg.

Vanity Fair said they had a hand in giving Winfrey an extra appendage and said they are correcting the mistake on their online covers, Entertainment Tonight reported.

The cover also features Robert De Niro, Tom Hanks, Zendaya, Harrison Ford and Nicole Kidman.

It also featured James Franco, but the publication admitted to digitally removing him after he became the focus of sexual misconduct allegations, The Daily Mail reported.

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