Hurricane Matthew, which has already killed more than 100 people and forced millions to flee from their homes, regained its status as a powerful Category 4 storm Thursday.

Matthew, described by Channel 2 Action News meteorologist Brian Monahan as the strongest storm in the Atlantic in a decade, prompted Gov. Nathan Deal to order a mandatory evacuation of six coastal Georgia counties and officials to close the eastbound ramps of I-16 near Dublin.

Deal’s order applies to more than 500,000 residents of Chatham, Bryan, Liberty, McIntosh, Glynn and Camden counties. He also called for the voluntary evacuation of residents of low-lying areas west of I-95.

After closing the eastbound ramps of I-16, the Georgia State Patrol issued a warning to drivers.

“The flow of traffic on I-16 will be converted to only WB as soon as the EB lanes have been cleared,” officials said in Twitter posts. “Don’t drive around traffic barriers. They’ve been put in place for your safety & the safety of other drivers.”

RELATED: See Hurricane Matthew’s projected path.

Just before 1 p.m., Matthew's death toll climbed to 108 in Haiti, up from a previous count of 23, The Associated Press reported. That raised the hurricane's overall toll across the Caribbean to 114.

Matthew was working its way through the Bahamas Thursday amid forecasters’ predictions it would be near Florida’s Atlantic coast by Thursday evening and reach coastal Georgia by Friday afternoon.

The eye of Matthew was about 125 from West Palm Beach, according to a 2 p.m. update from the National Weather Service.

Georgia has not had a direct hit from a hurricane in more than a century. The mandatory evacuation order and I-16 closure came a day after Deal expanded a state of emergency from 13 to 30 counties in the southeastern region of the state.

Governors in three other states — Florida, South Carolina and North Carolina — also declared states of emergency and issued evacuation orders. A motorist shot in an altercation with a South Carolina deputy over a Hurricane Matthew evacuation route died, The AP reported.

Government buildings were boarded up on Tybee Island, where a mandatory evacuation went into effect at 3 p.m. Wednesday. Chatham urged residents of all three islands and low lying areas east of the Wilmington River to evacuate starting at 8 a.m. All areas in and about rivers or tributaries were encouraged to evacuate, too.

“Any person that elects not to evacuate should be prepared to ride out the storm in a secure area with three days’ non- perishable provisions and adequate drinking water, given the potential for loss of power for 72 hours or greater,” authorities said.

Georgia’s state of emergency includes Appling, Atkinson, Bacon, Brantley, Bryan, Bulloch, Burke, Camden, Candler, Charlton, Chatham, Clinch, Coffee, Echols, Effingham, Emanuel, Evans, Glynn, Jeff Davis, Jenkins, Liberty, Long, McIntosh, Pierce, Screven, Tattnall, Treutlen, Toombs, Ware and Wayne counties. Coastal Georgia could get winds up to 70 mph, structural damage and widespread power outages.

Georgia Southern University in Statesboro and Savannah canceled all Friday and Saturday classes and events. Classes and events at Savannah Art of College and Design are canceled through Sunday. The school started evacuating students Thursday.

More than 2,500 flights have been canceled, according to ABC News.

There were 1,417 flights canceled Thursday alone, with 101 of those in Atlanta, the television network reported.

The Fort Lauderdale airport shut down Thursday and Orlando’s airport is expected to do the same later in the day.

Delta, American, United and JetBlue airlines are offering travelers change fee waivers for hurricane affected areas.

Matthew could also affect the University of Georgia’s football game against the University of South Carolina on Saturday night. School officials are monitoring the weather conditions to decide if they’re going to have to move the game or cancel it.

"We anticipate a decision about the game to be made on Thursday," South Carolina school officials said on Twitter. "The safety of everyone affected by the storm and the minimization of the impact on emergency personnel are the most important factors in making the decision."

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Map: Georgia preparations for Hurricane Matthew

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ATLANTA FORECAST

Today: Breezy. Mostly sunny. High: 81

Tonight: Mostly clear. Low: 64

Tomorrow: Mostly sunny. High: 78

» For a detailed forecast, visit The Atlanta Journal-Constitution weather page.

Even amid the hurricane threat along the Georgia Coast, expect dry, breezy and mostly sunny conditions Thursday in metro Atlanta.

“And while it’s not going to be really strong winds today, they’ll be picking up over the next day as that system gets closer to Georgia,” Channel 2 meteorologist Karen Minton said.

More clouds will cover parts of metro Atlanta as Hurricane Matthew approaches coastal Georgia, and the east side could get some rain.

A 20 percent rain chance is in effect for Friday.

Highs are expected to reach 81 degrees by 5 p.m. Thursday in Atlanta then drop to the upper 70s Friday.

Temperatures were 73 degrees in Atlanta, 75 in Blairsville and 73 in Griffin just before 1:20 p.m.