"When you die, it does not mean that you lose to cancer. You beat cancer by how you live, why you live and in the manner in which you live," Scott said on ESPN.

Despite all the ESPN anchor's airtime, USA Today said it was that speech that was his finest.

Scott first started his career in TV work after graduating from the University of North Carolina in 1988. He joined south Carolina’s WPDE and after a stint at local TV stations, he joined ESPN in 1993.

The ESPN anchor often cited his two daughters, Taelor and Sydni, as a big source of his motivation to keep fighting cancer.

Scott also maintained a close friendship throughout the years with ABC host Robin Roberts someone who also battled cancer.

“Chest hurts. Having trouble breathing,” Scott said.

“You’re alive,” Roberts said.

“I’m alive,” Scott said.

Fellow ESPN anchor Mike Tirico tweeted after hearing the news, "For those of us who live using words, today there are none. Our prayers to all who were touched by Stuart Scott's incredible love of life."

Scott is survived by his two teenage daughters.

This video includes images from Getty Images.