| Rank | Company | Founded | Ownership | Sector | Locations | Employees |
| 1 | Salesforce | 1999 | Public | Computer Software | 1 | 592 |
| 2 | Woodward Academy Inc | 1900 | Non-profit | Primary / Secondary School | 2 | 639 |
| 3 | Alston & Bird LLP | 1893 | Partnership | Law | 3 | 742 |
| 4 | Virtual Properties Realty | 1999 | Private | Agents / Brokers | 6 | 1649 |
| 5 | CarMax Auto Finance | 1993 | Public | Auto Dealership & Auto Finance Division | 7 | 1655 |
| 6 | Cancer Treatment Centers of America at Southeastern Regional Medical Center | 1988 | Private | Hospitals | 1 | 986 |
| 7 | IHG (InterContinental Hotels Group) Corporate Offices | 2003 | Public | Hotel | 3 | 1721 |
| 8 | KPMG LLP | 1897 | Partnership | Certified Public Accountants & Consultants | 3 | 1142 |
| 9 | Resurgens Orthopaedics | 1999 | Private | Physicians Practice | 21 | 855 |
| 10 | A.G. Rhodes Health & Rehab | 1904 | Non-profit | Healthcare - Skilled Nursing | 4 | 600 |
| 11 | Randstad USA | 1993 | Public | Staffing | 35 | 915 |
| 12 | Primerica, Inc. | 1977 | Public | Life Insurance, Annuities, & Retirement Investm... | 1 | 1615 |
| 13 | Equifax Inc. | 1899 | Public | Financial Services & Insurance | 3 | 2146 |
| 14 | Georgia-Pacific | 1927 | Private | Paper & Paper Products | 6 | 2849 |
| 15 | athenahealth | 1997 | Public | Heatlhcare IT | 1 | 508 |
| 16 | Clayton State University | 1969 | Public | College / University | 2 | 1182 |
| 17 | RaceTrac Petroleum, Inc | 1934 | Private | Convenience Store / Gas Station | 80 | 1699 |
| 18 | Manhattan Associates, Inc. | 1990 | Public | Supply Chain Management Software | 1 | 1207 |
| 19 | Northeast Georgia Health System | 1951 | Non-profit | Healthcare - Hospitals | 1 | 7350 |
| 20 | CareerBuilder | 1995 | Private | Recruitment Software | 1 | 681 |
| 21 | Greenway Health | 1977 | Private | Healthcare IT | 2 | 739 |
| 22 | Travelport | 1971 | Private | Technology Travel Business Services | 2 | 640 |
| 23 | Piedmont Healthcare | 1905 | Non-profit | Healthcare - Hospitals | 6 | 11777 |
| 24 | MarketSource | 1975 | Parent company | Business Process - Sales and Marketing Outsourcing | 2 | 605 |
| 25 | Sprint | 1938 | Public | Wireless Communication | 41 | 1463 |