This can make pain management challenging. Some physicians prescribe tramadol as an alternative, but it, too, can trigger dizziness and drowsiness.
Acetaminophen doesn’t have these sedating effects, though liver function should be monitored to prevent harm.
Q: I read your article on PPI drugs causing kidney trouble. I have been on Prilosec for years, so this definitely caught my attention.
You have not given us a way to get off these drugs, though. I was diagnosed with GERD — just too much acid. I want to get off Prilosec, but I need to know what replacement to try.
A: Researchers reported that proton-pump inhibitors are linked to kidney disease (JAMA Internal Medicine, February 2016). These powerful acid-suppressing drugs include dexlansoprazole (Dexilant), esomeprazole (Nexium), lansoprazole (Prevacid), omeprazole (Prilosec), rabeprazole (Aciphex) and pantoprazole (Protonix).
Other complications of long-term use can include mineral deficiencies, an increased risk for fracture, C. diff infections and pneumonia. Getting off such medications can sometimes be difficult due to rebound hyperacidity.
We are sending you our Guide to Digestive Disorders, which includes tips on getting off PPIs. Anyone who would like a copy, please send $3 in check or money order with a long (No. 10), stamped (71 cents), self-addressed envelope to: Graedons’ People’s Pharmacy, No. DJL-24, P.O. Box 52027, Durham, NC 27717-2027. It also can be downloaded for $2 from our website: www.peoplespharmacy.com.
The suggestions include gradually reducing the dose and/or the frequency of the drug and taking probiotics, antacids or herbs such as ginger or DGL (deglycyrrhizinated licorice).
Q: I suffered for many years with irritable bowel syndrome (IBS). At my annual physical, my cholesterol was a little high, so my doctor put me on fenofibrate to see if that would help. Within a week, I no longer had IBS symptoms.
After two years, I still have no IBS. My doctor was surprised but said she would mention it to other doctors.
A: We were a bit surprised too, since we had not heard this before. An online search uncovered a patent application for giving a fibric acid derivative such as fenofibrate to alleviate symptoms of IBS, so evidently others also have had benefit.