Low levels of the vitamin are common throughout the world. Data suggests that 23% of the people in Australia, 24% of people in the United States and 37% of people in Canada suffer deficiencies of the vitamin.
The researchers’ Mendelian study used a new genetic approach — nonlinear instead of linear — that allowed them to assess how increasing levels can affect cardiovascular disease risk based on how high the participants’ actual vitamin D levels were.
The study used information from 267,980 individuals, allowing the team to provide strong statistical evidence for the link between vitamin D deficiency and cardiovascular disease.
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