Some places will be exempt from the ban, including private residences, tobacco and vape stores, private clubs and cigar bars, and other establishments that ban minors and generate at least 20 percent of their annual gross revenue, or $250,000, from tobacco product sales.
Hartsfield-Jackson International Airport will close its smoking rooms on concourses as a result of the new ordinance.
In order to smoke, smokers on flights connecting in Atlanta will have to exit security during their layover to get to an outdoor terminal smoking area, then go back through security screening to return to the concourse.
Some restaurateurs and others voiced opposition to the ordinance at Atlanta City Council meetings.
But advocates said they wanted to protect public health, and said other places around the country have already adopted similar smoke-free ordinances. The city council on July 1 voted 13-2 in favor of the ordinance before sending it to the mayor for her signature.