Democrats saw Warnock as an outsider who could have helped excite the state's black electorate with a wholehearted embrace of President Barack Obama's initiatives. Several other potential candidates ruled themselves out, and several Democratic leaders rallied around him.
But his newcomer status and his plans to stay in the pulpit while also running for statewide office posed significant challenges. Questions swirled around whether he could maintain his day job without running afoul of Internal Revenue Service restrictions that prevent tax-exempt churches from actively engaging in political campaigns.
“Running for public office is a weighty affair and most often a life-changing journey,” said DuBose Porter, the head of the Democratic Party of Georgia. “Reverend Warnock’s journey has just begun, and Georgia Democrats look forward to working with him to make our state a better place.”
Any Democrat who challenges Isakson will face daunting odds in Georgia. The 70-year-old enjoys high name recognition, popularity across the aisle, solid relations with black leaders and more than $4 million in his campaign coffers.
But Isakson has also faced questions about his health since he revealed in June that he has suffered from Parkinson's for about two years. In that announcement, Isakson told reporters that the disease was in its earliest stages and that it would not jeopardize his ability to serve another six-year term.
That insistence hasn't stopped the rumors that he will not run — talk that Isakson's camp firmly denies. So far, he's only attracted one challenger: Republican Derrick Grayson, a MARTA engineer and minister who garnered 1 percent of the vote in the 2014 Senate primary.
Warnock's decision is a setback for Democrats who have struggled for months to find a viable candidate to challenge Isakson after last year's humbling defeats. The GOP swept every statewide office in 2014, and no Democrat topped 45.2 percent despite youthful candidates with brand-name political legacies.
After some leading Democrats passed on next year's Senate contest — state House Minority Leader Stacey Abrams, state Rep. Stacey Evans and former U.S. Rep. John Barrow were among those scouted for a run — Democratic operatives shifted their focus to Warnock.
Now that he’s ruled himself out, party leaders have reopened their conversations with another round of potential recruits. Among the names being floated are former Atlanta Mayor Shirley Franklin, state Rep. Scott Holcomb and Valarie Wilson, the head of the Georgia School Board Association and a former superintendent candidate.
Others, including former state Sen. Jason Carter, Atlanta Mayor Kasim Reed and Evans, have indicated they aren't interested.
The national party still has high hopes that it can find a high-profile candidate for the contest — someone who can also help the eventual Democratic presidential nominee turn out more voters. But the clock is ticking.
“Democrats are confident that we will find a great candidate in Georgia who will run a strong campaign and make this one of the most competitive races in the country,” said Justin Barasky of the Democratic Senatorial Campaign Committee. “The higher turnout that comes in presidential elections will be very advantageous.”