Every year, nonprofit Comic Relief Inc. holds an entertainment-focused fundraising campaign called Red Nose Day to raise money and awareness for children living in poverty around the world.

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Over the past four years, the campaign has raised nearly $150 million, with half of the funds distributed across the U.S. and the other half toward some of the poorest communities in Latin America, Asia and Africa.

This year, the campaign falls on Thursday, May 23.

The annual event will also feature a TV special on NBC hosted by Terry Crews and “the biggest names across entertainment.”

According to Parade, NBC's special is "a packed lineup of music, comedy and short documentary films that educate and engage viewers on the cause for the fifth annual event."

“This Is Us” star Milo Ventimiglia, who recently visited the outskirts of Nairobi, Kenya, as a part of the Red Nose Day campaign, will be sharing video of his encounters.

"Hopefully, people's familiarity with me and an interest in where I might be spending my time will lead to some good donations that are going to help kids out," he said.

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Some other big names to look out for: John Legend, Josh Groban, Kelly Clarkson, Michael Che, Colin Jost, Lilly Singh, Kate McKinnon, Connie Britton, Julia Roberts and more.

The Red Nose Special airs on NBC at 8 p.m. ET Thursday.

To participate yourself, buy your own $2 red nose at Walgreens or Duane Reade locations nationwide and “encourage your friends to get nosy about fundraising.”

"To recognize the fifth annual Red Nose Day, five collectable character Red Noses are joining the effort to keep children in the U.S and around the world safe, healthy and educated," according to a Walgreens news release last month. "Led by Red – the original Red Nose – newcomer Red Noses include Rojo, Ruby, Scarlet and Rusty each of whom has a special power to address serious issues affecting children living in poverty: illness, homelessness, hunger and illiteracy, respectively."

More about the campaign at rednoseday.org.

The Associated Press contributed to this report.