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When researchers compared markers between the younger and older mice, they found the latter had higher amounts of the modified histone protein H3K79me3.
In earlier research from the same graduate school, also led by Osumi, “found a correlation between the amount of H3K79me3 in sperm and abnormal speech communication in pups, making it a predictive marker of neural-developmental disorders.”
The new study suggests that paternal aging potentially affects neurodevelopment in humans.
“In other words, the older the parent, the increased risk a child has of developing disorders such as autism, ADHD and other learning disabilities,” researchers wrote.
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