If radiation and chemo don’t work on brain cancer, what’s next?

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John McCain Diagnosed With Brain Cancer

Most patients with glioblastoma, the same brain cancer Sen. John McCain has, begin their medical treatment with radiation and chemotherapy. Many times, however, the cancer returns.

What are patients’ options after all known treatments have failed? The answer could be in one of dozens of clinical trials throughout the country looking for new ways to fight cancer.

Immunotherapy, vaccines, medications and a combination of these treatments are being studied.

Suzanne Stone of Texas was diagnosed with glioblastoma more than two years ago and has undergone chemo, radiation and — when the cancer returned — surgery. She knows what McCain and his family are going through, she said. "My message to him is, 'Just don't give up.'”

The full story on clinical trials and how doctors are hoping to treat cancer can be read at myajc.com.