For its study, the researchers linked administrative databases from ICES (formerly called the Institute for Clinical Evaluative Services) in Ontario. They included “all community‐dwelling individuals aged 66 and older who underwent one of five elective surgical procedures in Ontario, Canada, between April 1, 2007, and March 31, 2011. Individuals with evidence of dementia preceding cohort entry were excluded. Individuals who received GA were matched within surgical procedures to those who received RA on age, sex, cohort entry year, and a propensity score to control for potential confounders.”
In all, 7,499 matched pairs were included in the final analysis. The researchers found no difference in the risk of being diagnosed with dementia for individuals who received general anesthesia when compared with regional anesthesia. “There was also no association between anesthesia and dementia in most subgroup and sensitivity analyses,” they wrote.