Borland, 24, led his team with 108 tackles in his rookie season, emerging as a standout on defense. He had a sack and two interceptions.

Borland told "Outside the Lines" he wants to do "what's best for my health."

The 49ers have taken several hits recently.

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Last week, five-time All Pro linebacker Patrick Willis announced his retirement. The team lost coach Jim Harbaugh after the season,  then watched Frank Gore, Mike Iupati, Chris Culliver and Perrish Cox depart in free agency this past week.

AP contributed to this report.