Try, try again.

The Powerball jackpot is up to an estimated $400 million, with a $223.6 million cash-option value, after no one matched all six numbers in Saturday night’s drawing, according to the lottery website.

The five numbers drawn in the multi-state game were 1, 17, 25, 37 and 44, with a Powerball of 20.

Saturday’s Powerball jackpot stood at $317 million, with a cash option of more than $176 million, after no one matched all six numbers in Wednesday’s drawing.

Five winners, one each in Georgia, Indiana, Massachusetts, Maine and New York, took home $1 million each after winning on Wednesday, but no one matched all five numbers — 11, 19, 33, 42 and 52, with a Powerball of 33 — to win it all.

The Powerball jackpot peaked at $590 million in May — the largest jackpot in the multi-state game’s history, and the second-largest jackpot in U.S. history, according to Georgia Lottery officials.

Floridian Gloria Mackenzie, 84, held the winning ticket, and took home a $331 million cash payout.

The odds of winning the jackpot are one in 175 million.

The next drawing is Wednesday.