Thursday’s game

Clemson at Louisville, 7:30 p.m., ESPN

Friday’s game

Florida State at Boston College, 8 p.m., ESPN

Saturday’s games

Illinois at North Carolina, noon, ESPN2

Wake Forest at Army, noon, CBS Sports Network

Northwestern at Duke, 12:30 p.m., WUPA

Central Michigan at Syracuse, FSSO, 12:30 p.m.

Georgia Tech at Notre Dame, 3:30 p.m., NBC

Nebraska at Miami, 3:30 p.m., ABC

William & Mary at Virginia, 3:30 p.m.

Virginia Tech at Purdue, 3:30 p.m., ESPNU

N.C. State at Old Dominion, 7 p.m.

Pittsburgh at Iowa, 8 p.m., Big Ten

Louisville’s turnovers are mounting, the defense is rebuilding and coach Bobby Petrino can’t decide on a quarterback.

Those factors have contributed to the Cardinals’ 0-2 start, the first time they’ve been winless after two games since 1998.

Petrino has played freshman Lamar Jackson, Kyle Bolin and Reggie Bonnafon at quarterback and will continue to let the nation play a guessing game as to who will start against Clemson, he said on Wednesday’s ACC teleconference.

He won’t announce a starter until game time.

The quarterbacks contributed to three interceptions and lost a fumble in the loss to Houston. The Cardinals had two turnovers against Auburn.

“Offensively, the No. 1 thing we need to do is eliminate the turnovers and the timing of the turnovers,” Petrino said.

Bonnafon started in the opener, but Jackson also played and led the Cardinals with 106 yards rushing.

Jackson started against Houston and threw for 127 yards, but with two interceptions, and was replaced by Bolin, who threw for 157 yards and sparked Louisville to two fourth-quarter touchdowns.

“Kyle came in last week and operated the offense,” Petrino said. “He understands how the offense works, and his experience shows. He was able to distribute the ball and allow us to move it down and get a couple touchdowns.”

Will Gardner (Coffee), who started seven games in 2014 before tearing his left ACL, hasn’t played this year.

Quarterback isn’t a problem at Clemson.

Deshaun Watson has thrown for 442 yards and five touchdowns against lesser opponents (Wofford and Appalachian State), but will be without center Ryan Norton (knee) and top receiver Mike Williams (neck).

“Louisville is a good team. I know everybody is talking about how they’re 0-2 right now,” Clemson coach Dabo Swinney said. “Well I wouldn’t look too much into that. Louisville is a good football team that I have no doubt will be in a bowl game at the end of the year, and they have the same chance that we have to win this division.”

Cook on the loose: There's no keeping this cook in the kitchen.

Florida State running back Dalvin Cook averaged 169.2 yards rushing in his past five games, thanks in part to his 266 yards in Saturday’s victory over South Florida.

That is the highest single-game total in the FBS this season and the most in the ACC since Boston College’s Andre Williams had 339 yards Nov. 16, 2013.

“Look at the results. And also body,” coach Jimbo Fisher said. “I asked him (Monday), how do you feel? He said, ‘Coach, I feel fine.’ Some guys can’t take that wear and tear. His body feels really good.”

Fisher said he hadn’t planned for Cook to have 30 carries, but continued to give him the ball until he scored the final touchdown on a 37-yard run with 1:55 left in the fourth quarter.

Backup Mario Pender had only seven carries.

“We don’t do that all the time, but we’ll do it if we have to,” Fisher said. “(Cook has) got to get his touches in the game. If he’s hot like that and he can finish, we’re going to continue to give it to him.”

The Seminoles have a 24-game ACC winning streak heading into Friday’s game at Boston College.

Deacons driving: Wake Forest ranked last in the FBS in total offense last season with an average of 216.3 yards per game.

The Demon Deacons rushed for a total of 479 yards in 12 games in 2014 and averaged a 1.3 yards per carry. They already have 249 rushing yards this season and have made even more strides through the air.

Quarterback John Wolford has thrown for 696 yards, and Wake Forest leads the ACC in passing offense, with 380.5 per game.

The competition has been Elon and Syracuse, but the improvement is evident as the Demon Deacons rank 23rd in the FBS in total offense, with 505 yards per game.

“Those rankings are cool to see, but ultimately it comes down to wins and losses,” Wolford said. “That’s the most important stat, and we’ve got to continue to win. Obviously, we don’t accept losing. It’s good to see that we’re making strides statistically, but we’ve got to put it on the field and put it together so we can win those games.”

He said it: "Adversity strikes at all times, any place. You guys know the personal stories, the life stories and stuff like that. But there's got to be a model, hopefully to the players, of resiliency. I believe I'm a resilient guy. I understand the importance of this season and what's going on. If I don't model that to these guys, I don't know who will." — Virginia coach Mike London

Etc.: Florida State's Roberto Aguayo set the ACC record with 161 consecutive extra-point attempts. … There were 18 former ACC quarterbacks on NFL rosters through Sept. 8, the most of any conference. … Pittsburgh receiver Tyler Boyd, who was suspended for the opener, caught 11 passes for 96 yards in a victory over Akron. He had more than 1,000 yards receiving in each of his first two seasons. … N.C. State quarterback Jacoby Brissett has completed 84.4 percent of his attempts to lead the FBS. He is 38-of-45 for 412 yards and three touchdowns. … Boston College allowed only 11 yards in its 76-0 win over Howard, setting the single-game ACC mark.