Twelve people were killed in accidents over the Labor Day weekend, the Georgia Department of Public Safety said.

“Don’t drink and drive,” the agency said in a Twitter post.

Police are investigating if alcohol was a factor in at least two of the fatal crashes. Both shut down traffic on I-75 Sunday in Atlanta.

Jose Castro-Villatoro, 40, clipped a car near the Downtown Connector and Williams Street about 1:30 a.m. Police said he was driving a Toyota 4Runner at “a high rate of speed when he attempted to change lanes to avoid several vehicles that had stopped in the roadway due to a broken down vehicle,” Atlanta police said in an email.

The driver suffered major trauma and died on the scene. The driver of the second vehicle was taken to Atlanta Medical Center for minor injuries and is expected to be OK, police said.

A second accident left a man dead and shut down lanes on I-75 near Mount Paran Road about 4 a.m.

Police said a driver of a 2002 Acura MDX was headed north on the interstate when the driver drifted off the roadway and struck the guardrail.

When he got out of the SUV, a car struck and killed him. The Fulton County Medical Examiner’s Office officials identified the man as Jude May, 40, of Atlanta.