1. Candidates spar over taxes, emails. In one of the most heated exchanges of the night, the candidates clashed over two big issues: Trump's refusal to release his tax returns and Clinton's email scandal.

>> PHOTOS: Clinton, Trump face off in first debate

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2. Clinton fires back after Trump questions her stamina. When asked to weigh in on his recent comment that Clinton doesn't have "a presidential look," Trump responded, "She doesn't have the look. She doesn't have the stamina. I said she doesn't have the stamina. And I don't believe she does have the stamina. To be president of this country, you need tremendous stamina."

>> Trump sniffing at the debate gets a lot of attention on Twitter

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3. Clinton defends her debate preparation. While discussing African-American communities and his visits to Detroit and Philadelphia, Trump slammed Clinton's recent absence from the campaign trail, saying, "I've been all over the place. You decided to stay home, and that's OK."

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4. Trump says "why not" blame Clinton for all the country's problems. After Trump laid into Clinton on economic issues, she joked, "I have a feeling that by the end of this evening, I'm going to be blamed for everything that's ever happened."

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5. Trump lauds his temperament. When asked how his judgment is different from Clinton's, Trump said, "Well, I have much better judgment than she does. There's no question about that. I also have a much better temperament than she has, you know?"

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