About 650 adults will spend Saturday searching Atlanta as part of a city-wide scavenger hunt to benefit children with cancer.

The Great Urban Race is a fundraiser for St. Jude Children’s Research Hospital. Teams will solve 12 clues by solving puzzles and completing physical challenges. The first 25 teams to finish will have the opportunity to compete in the national championship in New Orleans, race officials said.

Participants must pay $55 per person or $65 on race day. Of that money, $10 will go to St. Jude’s. To register, visit www.greaturbanrace.com.