A suspected U.S. drone strike killed the No. 2 commander of the Pakistani Taliban on Wednesday, Pakistani intelligence officials said, although the militant group denied he was dead.

If confirmed, the death of Waliur Rehman would be a strong blow to the militant group responsible for hundreds of bombings and shootings across Pakistan. The United States has a $5 million bounty out on Rehman, who Washington has accused of involvement in the 2009 suicide attack on a U.S. base in Afghanistan that killed seven Americans working for the CIA.

Early Wednesday, missiles fired by a U.S. drone slammed into a home in Miran Shah, the main town of the North Waziristan tribal region, killing five people including Rehman, Pakistani officials said.

Two officials said their informants in the field saw Rehman’s body, while a third said intelligence authorities had intercepted communications between militants saying Rehman had been killed. The officials spoke on condition of anonymity because they were not authorized to brief reporters.

A spokesman for the Pakistani Taliban denied the reports.

“This appears to me to be false news. I don’t have any such information,” said Ahsanullah Ahsan.

White House spokesman Jay Carney declined to confirm if Rehman was dead. He said if the reports were true, Rehman’s death would deprive the militant group of its chief military strategist involved in “horrific attacks” on a CIA base in Afghanistan and other attacks against Pakistani civilians and soldiers.

Most of North Waziristan is under militant control, and journalists cannot access the rugged region near the Afghan border, making independent confirmation difficult.

The missile attack was the first since Pakistan’s May 11 elections in which the American drone program was a hotly debated topic.

It was also the first strike in Pakistan since President Barack Obama’s speech last Thursday in which he discussed more restrictive rules he was implementing on drone use in places such as Pakistan and Yemen.

The tribal region in northwestern Pakistan is home to local and Afghan militant outfits, including al-Qaida-linked fighters. The U.S. has often criticized Pakistan, saying it does not vigorously target militants in these areas who then attack American troops in Afghanistan.

Pakistani officials say their military is already overtaxed fighting militants in the tribal regions and in the southwestern province of Baluchistan, and that the casualties they’ve already incurred have not been properly recognized.

Washington’s drone program remains deeply unpopular in Pakistan, even though the number of strikes has dropped significantly since the height of the program in 2010. The strikes usually target al-Qaida-linked insurgents or other militants who fight in Afghanistan, although some strikes have killed militants at war with the Pakistani government.

The Pakistani Taliban, officially called the Tehrik-e-Taliban, has been battling government forces for years in a bid to push them from the tribal regions, cut Pakistan’s ties with the U.S. and eventually establish their brand of hardline Islam across Pakistan.

Rehman has been on the U.S. radar for years. While Rehman was mostly known for his activities in Pakistan, he also participated in cross-border attacks in Afghanistan against U.S. and NATO personnel.

The U.S. wanted Rehman in connection with his alleged involvement in an attack on a U.S. base in Khost, Afghanistan in 2009. The attack on Camp Chapman killed seven Americans working for the CIA, a Jordanian intelligence officer and wounded six other CIA personnel.