As you might expect, social media reaction was mixed toward the CDC’s new mask guidelines.

The CDC’s new guidance announced Thursday allows COVID-vaccinated people to ditch their masks indoors in many instances.

The CDC still is calling for wearing masks in crowded indoor settings such as buses, planes and hospitals but eased restrictions for reopening workplaces and schools.

Here is a sample of responses on Twitter:

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Fans celebrate in the stands after Cape Verde defeated Eswatini in a World Cup qualifying soccer match at Estádio Nacional in Praia, Cape Verde, Monday, Oct. 13, 2025, to clinch their qualification for the 2026 World Cup. (Cristiano Barbosa/AP)

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