Police said early Saturday that white powdery substance sent to Hillary Clinton's campaign office in New York tested negative for harmful substances in a preliminary investigation, CNN reported.

Clinton campaign workers had opened an envelope containing the white substance Friday, police said.

The envelope had first been delivered to Clinton's midtown Manhattan office, Lt. Thomas Antonetti of the New York Police Department said. It was then transferred to her Brooklyn headquarters.

Workers evacuated the 11th floor of the Brooklyn office in the evening. Police would not say what the substance was, but told The Associated Press that it was not harmful.

The initial report indicated that the envelope had been opened in the Manhattan office and then passed on to Clinton’s headquarters in Brooklyn. It wasn't clear why the opened envelope had been transferred.

The NYPD is investigating the incident. The Secret Service and the Office of Emergency Management are also involved, a NYPD spokesman said.