A suspicious letter mailed to the White House was similar to two threatening, poison-laced letters on the gun law debate sent to New York Mayor Michael Bloomberg, one of the nation’s most potent gun-control advocates, officials said Thursday.

The Secret Service said the letter was addressed to President Barack Obama and was intercepted by a White House mail screening facility. Two similar letters postmarked in Louisiana and sent to Bloomberg in New York and his gun control group in Washington contained traces of the deadly poison ricin.

It wasn’t immediately clear whether the letter sent to Obama contained ricin. It was turned over to the FBI’s Joint Terrorism Task Force for testing and investigation.

The two Bloomberg letters, opened May 24 in New York and Sunday in Washington, contained an oily pinkish-orange substance.

New York Police Department Commissioner Raymond Kelly said Thursday all three letters apparently came from the same machine or computer and might be identical, but referred specific questions to the FBI.

The body of the letter mailed to New York was addressed to “you” and referenced the gun control debate. Kelly said the unsigned letter says, in so many words: “Anyone who comes for my guns will be shot in the face.” He refused to quote directly from the letter, saying he didn’t want to do the author’s bidding.

Bloomberg has emerged as one of the country’s most important gun-control advocates, able to press his case with both his public position and his private money.

The New York letter was opened at the city’s mail facility in Manhattan in a biochemical containment box, which is a part of the screening process for the mayor’s office mail.

“In terms of the processes and procedures that are in place now, we think they worked,” Kelly said. “This is sort of an effect of the post-9/11 world that we live in that these checks and facilities are in place, and the system worked.”

The second letter was opened Sunday by Mark Glaze, director of Mayors Against Illegal Guns, the Washington-based nonprofit Bloomberg started.

The letter Glaze opened tested positive for ricin initially. The other letter to Bloomberg at first tested negative but tested positive at a retest Wednesday.

The postal workers union, citing information it got in a Postal Service briefing, said the letters bore a Shreveport, La., postmark. Kelly would not comment on the origin of the letter.

Louisiana State Police spokeswoman Julie Lewis said state authorities have deferred to the FBI and have not opened an investigation. The Shreveport postal center handles mail from Louisiana, Texas and Arkansas, so the letter could have come from any of those states, Lewis said.

The people who initially came into contact with the letters showed no symptoms of exposure to the poison, but three officers who later examined the New York letter experienced minor symptoms that have since abated, police said. The mayor visited the mailroom Thursday but made no public comments on the topic.

On Wednesday, he said he didn’t know why they were sent.

One of the letters “obviously referred to our anti-gun efforts, but there’s 12,000 people that are going to get killed this year with guns and 19,000 that are going to commit suicide with guns, and we’re not going to walk away from those efforts,” said Bloomberg, adding that he didn’t feel threatened.

According to the federal Centers for Disease Control and Prevention, ricin is a poison found naturally in castor beans. Symptoms can include difficulty breathing, vomiting and redness on the skin depending on how the affected person comes into contact with the poison.