Vice President Joe Biden's oldest son has died after a fight with brain cancer. Beau Biden was 46 years old.

Beau Biden had been diagnosed with brain cancer in 2013, at a time he'd been considering making a run for governor of Delaware. (Video via BarackObama.com)

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His speech at the 2008 Democratic National Convention introducing his father was moving and personal, and launched him onto the national stage.

A statement from the office of the vice president called the former Delaware attorney general "the finest man [the Biden family have] ever known."

Beau Biden is survived by his wife and two children.

This video includes images from Getty Images.

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