The college started with 118 students and now enrolls nearly 9,400.
An interim president and information on a search committee will be announced at a future date, said John Millsaps, a spokesman for the University System of Georgia.
The move marks another career change for Kaufman. The retired U.S. Army brigadier general previously served as the chief academic officer for the U.S. Military Academy at West Point, N.Y.
The chamber’s chairman, Phil Wolfe, said in a statement that Kaufman is one of the “nation’s premier executives who possesses the business acumen and strategic visioning to successfully position this organization for future growth.”