While sexually transmitted diseases (STDs) pose a significant health challenge across the U.S. with nearly 20 million new infections annually, the challenge is greater in some cities, according to a recent report.

RentApplication.com mapped the top 100 most sexually diseased cities across the country, measuring the number of reported cases of syphilis, gonorrhea and chlamydia (herpes excluded) per 100,000 people.

Top 10 most sexually diseased cities 

1. Montgomery, Ala.

2. St. Louis, Mo.

3. West Memphis, Ariz.

4. Philadelphia, Pa.

5. Norfolk, Va. (Norfolk Naval Base)

6. Baltimore, Md.

7. Richmond, Va.

8. New Orleans, La.

9. Killeen, Tx. (Ft. Hood)

10. Fayetteville, N.C. (Ft. Bragg)

About the Author

Keep Reading

Featured

A person exits the Wolf Creek Library in Atlanta after casting his ballot during election day on Tuesday, Nov. 4, 2025. (Miguel Martinez/AJC)

Credit: Miguel Martinez/AJC