A wreck Tuesday afternoon involving multiple vehicles and a tractor-trailer has all but one lane of I-85 southbound blocked just before I-285, according to the Georgia DOT.

Four of five lanes were blocked around 3:45 p.m. Emergency responders are the scene, but it was not immediately known if injuries were reported.

Drivers are advised to avoid the area, if possible.

For the latest traffic updates, follow @ajcwsbtraffic on Twitter.

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Waymo autonomous vehicles operate across 65 square miles inside I-285 and have been involved in six incidents with Atlanta Public School buses since May. Waymo issued a recall because of their cars briefly stopping or slowing down before continuing forward while a bus was stopped and flashing its lights. (Courtesy of Atlanta Public Schools)

Credit: Courtesy of Atlanta Public Schools