A small plane crashed near California’s John Wayne Airport on Friday morning, sending plumes of dark smoke into the air and leaving two people hospitalized, according to multiple reports.

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Airport officials said in a tweet that a Cessna 310 landed short of the runway near Interstate 405 in Orange County around 9:35 a.m. Debris from the crash prompted officials to close the interstate as they worked to clear the road and officials at John Wayne Airport briefly closed to arrivals.