A man was killed in a fiery two-car crash that shut down a major artery in Smyrna for more than six hours Friday, police said.

An orange 2009 Dodge Challenger was driving more than 100 mph on eastbound Windy Hill Road when it collided with a gray 1979 Chevrolet Monte Carlo heading northbound on Atlanta Road about 1:24 a.m., Smyrna police said. The Monte Carlo, which was entering the intersection with Windy Hill Road at the time of the crash, exploded and split in half. The driver, 26-year-old Osornio Guadalupe of Smyrna, died on the scene.

A passenger in the Challenger was taken to WellStar Kennestone Hospital with injuries described as serious. The driver had non-life-threatening injuries.

“We could tell that speed was a factor,” Smyrna police spokesman Louis Defense said. “All the other attributes to what happened are still under investigation.”

Windy Hill Road, which many people use to get to I-75, was blocked near Atlanta Road.

All lanes on Windy Hill have reopened, according to the WSB 24-hour Traffic Center.

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— Photographer Branden Camp contributed to this article.