The school is located at 10336 Wilson Blvd. in Blythewood, near Exit 24 on Interstate 77.
When deputies arrived, they found the babies inside a vehicle, and both died at the scene, according to the sheriff’s department.
More information about the babies, including their names, was expected to be released during a news conference held by the coroner’s office once the autopsies were complete.
The sheriff’s department said it was unclear whether there was any involvement by the staff of Sunshine House, but the deaths remain under investigation.
Sunshine House of Blythewood has been open for more than 45 years, according to its website.