The research was done on rats.

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The drug changed the way fat was metabolized and triggered extreme inflammation and a corresponding sharp rise in the formation of ceramides; those are the molecules that cause cells to age and die.

“We found this signaling process to be key for advanced cellular aging, which is at the heart of the accelerated aging influenced by methamphetamine abuse,”Piomelli said.

Methamphetamine is highly addictive drug, in part because it gives users a feeling of euphoria.

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Tracy Woodard from InTown Cares (left) and Lauren Hopper from Mercy Care organization work with residents at the Copperton Street encampment in August 2024. 
(Miguel Martinez / AJC)

Credit: Miguel Martinez