Grammy Award-winning R&B singer James Ingram has died from brain cancer at the age of 66, according to news reports.

>> Read more trending news

Legendary music producer Quincy Jones called Ingram his “baby brother” and said “there are no words to convey how much my heart aches.”

Longtime friend Debbie Allen confirmed the tragic news earlier on social media.

“I have lost my dearest friend and creative partner James Ingram to the Celestial Choir,” she posted. “He will always be cherished, loved and remembered for his genius, his love of family and his humanity. I am blessed to have been so close,” she said.

Ingram, an Ohio native, was a huge R&B star during the 1980s and 90s with hits like “Baby Come to Me,” “I Don’t Have the Heart,” “Just Once” and “One Hundred Ways.”

He was a two-time Grammy Award winner and a two-time Oscar nominee who collaborated with big name stars like Jones, Ray Charles, Anita Baker, Michael Jackson and Michael McDonald, to name a few.

Ingram is survived by his wife, Debra Robinson, according to WJW-TV.

R&B Singer James Ingram performs on 'The Hippest Trip At Sea' Soul Train Cruise on February 26, 2015, during a cruise that departed from Fort Lauderdale, Florida, and traveled to Turks & Caicos Islands, Puerto Rico, US Virgin Islands and the Bahamas.

Credit: Earl Gibson III

icon to expand image

Credit: Earl Gibson III