For more than 30 years one drug, metronidazole (Flagyl or generic), has been the standard treatment for trichomoniasis. These days, the drug tinidazole (Tindamax) is also used. In most cases, infection is cured in women with a single oral dose of two grams of either of the two drugs, both of which are in a class called 5-nitroimidazole drugs and are prescription drugs. Pregnant women may be treated with metronidazole. There is no reason for a follow-up visit if you do not have symptoms after the treatment or if you had no symptoms before treatment. For those who fail treatment, longer courses of metronidazole or tinidazole are recommended by the Centers for Disease Control and Prevention (CDC), usually another single two-gram dose of tinidazole or 500 milligrams twice a day for five days of metronidazole. If this second course of medication fails, the CDC recommends two grams per day for five days of either metronidazole or tinidazole.

You should take metronidazole or tinidazole with food and avoid drinking alcohol while taking either medication and for three days after.

It is important that your sex partner also be treated; otherwise reinfection is likely. Sexual contact should be avoided until both partners are treated.